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Li-Mei Chen Selected Research

prostasin

6/2021Prostasin regulates PD-L1 expression in human lung cancer cells.
1/2021Prostasin regulates PD-L1 expression in human lung cancer cells.
12/2015Ibuprofen regulates the expression and function of membrane-associated serine proteases prostasin and matriptase.
12/2009Prostasin regulates iNOS and cyclin D1 expression by modulating protease-activated receptor-2 signaling in prostate epithelial cells.
10/2009Loss of prostasin (PRSS8) in human bladder transitional cell carcinoma cell lines is associated with epithelial-mesenchymal transition (EMT).
5/2008The epidermal growth factor receptor (EGFR) is proteolytically modified by the Matriptase-Prostasin serine protease cascade in cultured epithelial cells.
7/2007Prostasin induces protease-dependent and independent molecular changes in the human prostate carcinoma cell line PC-3.
9/2006Prostasin attenuates inducible nitric oxide synthase expression in lipopolysaccharide-induced urinary bladder inflammation.
8/2006Mechanisms of sterol regulatory element-binding protein-2 (SREBP-2) regulation of human prostasin gene expression.
6/2006Androgen regulation of prostasin gene expression is mediated by sterol-regulatory element-binding proteins and SLUG.
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Li-Mei Chen Research Topics

Disease

25Human Influenza (Influenza)
03/2021 - 05/2008
16Neoplasms (Cancer)
11/2022 - 01/2002
10Infections
03/2021 - 01/2009
8Influenza in Birds (Avian Flu)
03/2021 - 05/2008
7Breast Neoplasms (Breast Cancer)
11/2022 - 01/2002
5Inflammation (Inflammations)
06/2021 - 09/2006
5Prostatic Neoplasms (Prostate Cancer)
07/2010 - 01/2002
4Urinary Bladder Neoplasms (Bladder Cancer)
12/2015 - 10/2009
3Carcinoma (Carcinomatosis)
05/2008 - 01/2002
2Lung Neoplasms (Lung Cancer)
06/2021 - 01/2021
2Carcinogenesis
06/2021 - 01/2021
2Colorectal Neoplasms (Colorectal Cancer)
02/2020 - 01/2017
2Body Weight (Weight, Body)
09/2018 - 08/2017
2Orthomyxoviridae Infections
01/2018 - 04/2011
2Multiple Myeloma
04/2016 - 06/2005
2Transitional Cell Carcinoma
12/2015 - 10/2009
1Triple Negative Breast Neoplasms
11/2022
1Treatment-Resistant Depressive Disorder
10/2021
1Rheumatoid Arthritis
01/2021
1Cardiovascular Diseases (Cardiovascular Disease)
01/2021
1Neoplasm Metastasis (Metastasis)
01/2021
1Myocardial Ischemia (Ischemic Heart Diseases)
01/2021
1Dental Caries (Decay, Dental)
02/2020
1Non-alcoholic Fatty Liver Disease
03/2019
1Neuroblastoma
01/2019
1Fibrosis (Cirrhosis)
01/2019
1Invasive Candidiasis
09/2018
1Hepatic Insufficiency
09/2018
1Acute Promyelocytic Leukemia
06/2018
1Obesity
08/2017
1Ataxia Telangiectasia (Louis Bar Syndrome)
01/2017

Drug/Important Bio-Agent (IBA)

15VaccinesIBA
03/2021 - 02/2003
13prostasinIBA
06/2021 - 01/2002
10Hemagglutinins (Hemagglutinin)IBA
03/2021 - 09/2008
10Proteins (Proteins, Gene)FDA Link
08/2017 - 01/2002
7Serine Proteases (Serine Protease)IBA
06/2021 - 01/2002
5matriptaseIBA
01/2019 - 05/2008
4AntibodiesIBA
01/2019 - 01/2009
4CytokinesIBA
01/2019 - 09/2006
4Neuraminidase (Sialidase)IBA
11/2012 - 01/2009
3LipopolysaccharidesIBA
06/2021 - 09/2006
3Influenza Vaccines (Influenza Vaccine)FDA Link
05/2014 - 02/2011
3Messenger RNA (mRNA)IBA
07/2011 - 01/2002
3Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA
10/2009 - 08/2006
2AntioxidantsIBA
11/2022 - 02/2020
2Interleukin-6 (Interleukin 6)IBA
11/2022 - 01/2017
2Reactive Oxygen Species (Oxygen Radicals)IBA
11/2022 - 02/2020
2Therapeutic UsesIBA
01/2021 - 01/2017
2Biological ProductsIBA
07/2020 - 05/2008
2fucoidanIBA
02/2020 - 01/2017
2Biomarkers (Surrogate Marker)IBA
01/2019 - 09/2014
2AntigensIBA
09/2015 - 07/2006
2N-Acetylneuraminic Acid (Sialic Acid)IBA
01/2013 - 05/2008
2nasIBA
11/2012 - 03/2012
2Peptide Hydrolases (Proteases)FDA Link
07/2010 - 07/2007
2Epidermal Growth Factor (EGF)IBA
05/2008 - 06/2006
1LigandsIBA
06/2021
1triptolideIBA
01/2021
1Pharmaceutical PreparationsIBA
01/2021
1Isoproterenol (Isoprenaline)FDA LinkGeneric
01/2021
1Volatile Oils (Essential Oils)IBA
01/2021
1Oxidoreductases (Dehydrogenase)IBA
01/2021
1Superoxide DismutaseIBA
01/2021
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
01/2021
1B7-H1 AntigenIBA
01/2021
1Estrogens (Estrogen)FDA Link
07/2020
1Estradiol Congeners (Synthetic Estrogens)IBA
07/2020
1ResveratrolIBA
07/2020
1Diethylstilbestrol (Stilbestrol)FDA Link
07/2020
1Cisplatin (Platino)FDA LinkGeneric
02/2020
1Superoxides (Superoxide)IBA
02/2020
1Tobacco Smoke Pollution (Passive Smoking)IBA
02/2020
1FluoridesIBA
02/2020
1myricetinIBA
03/2019
1Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
01/2019
1Cadherins (E-Cadherin)IBA
01/2019
1Estrogen ReceptorsIBA
01/2019
1EchinocandinsIBA
09/2018
1Antifungal AgentsIBA
09/2018
1Caspofungin (Cancidas)FDA Link
09/2018
1AzolesIBA
09/2018
1Arsenic Trioxide (Trisenox)FDA Link
06/2018
1HGF activatorIBA
08/2017
1phorbolIBA
08/2017
1MicroRNAs (MicroRNA)IBA
08/2017
1iodothyronine deiodinase type IIBA
08/2017
1Thyroid HormonesIBA
08/2017
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
01/2017
1Checkpoint Kinase 1IBA
01/2017
1IsotopesIBA
01/2017
1Etoposide (VP 16)FDA LinkGeneric
01/2017
1Bortezomib (Velcade)FDA Link
04/2016
1Dexamethasone (Maxidex)FDA LinkGeneric
04/2016
1Lenalidomide (CC 5013)FDA Link
04/2016
1Ibuprofen (Motrin)FDA LinkGeneric
12/2015

Therapy/Procedure

4Drug Therapy (Chemotherapy)
02/2020 - 06/2005
2Therapeutics
09/2018 - 11/2009
1Vagus Nerve Stimulation
10/2021
1Resuscitation
01/2021